Senior Regulatory Affairs Pharmacist
Premium Ad Professions - Other Professions Johannesburg FULL TIME Job Summary A leading pharmaceutical organisation is seeking an experienced Senior Regulatory Affairs Pharmacist to join their Regulatory Affairs team. The successful candidate will be responsible for managing regulatory activities, ensuring compliance with applicable legislation, supporting product registrations, and overseeing lifecycle management activities across the product portfolio. This role requires strong technical regulatory knowledge, excellent attention to detail, and the ability to manage regulatory submissions while collaborating with internal and external stakeholders. Key Responsibilities * Ensure compliance with SAHPRA legislation, the Medicines and Related Substances Act, the Pharmacy Act, and relevant regulatory guidelines. * Monitor regulatory changes and communicate potential business impacts. * Maintain effective relationships with regulatory authorities and key stakeholders. * Compile, review, and submit CTD/eCTD dossiers for: + New product registrations + Variations + Renewals + Transfers of ownership + Other regulatory submissions * Prepare responses to regulatory authority queries and deficiency letters. * Manage product lifecycle activities, including: + PI/PIL updates + Labelling changes + Packaging updates + Approved variations * Maintain accurate regulatory records, submission trackers, and document management systems. * Provide regulatory support for product launches and lifecycle projects. * Review promotional materials, artwork, labels, packaging components, and product information for compliance. * Collaborate with internal teams, including Marketing, Supply Chain, Manufacturing, and New Business Development. * Provide technical guidance, mentoring, and support to Regulatory Affairs team members. * Assist with improving regulatory processes, systems, and operational efficiencies. Requirements * B.Pharm degree. * Current registration with the South African Pharmacy Council (SAPC). * Minimum 5 years’ Regulatory Affairs experience within the pharmaceutical industry. * Minimum 2 years’ experience specifically within Regulatory Affairs Pharmacist responsibilities. * Strong knowledge of: + SAHPRA requirements + CTD/eCTD submissions + Product registration processes + Product lifecycle management…
Gauteng is an important market for jobs and professional roles in South Africa. Gauteng concentrates head-office roles, banking, retail, logistics, and public-sector vacancies. Competition is high, so applying early and tailoring each CV matters more than sending one generic document everywhere. Finance, IT, call centres, retail management, and mining services dominate hiring. Students often find internships and learnerships through large employers with structured intake seasons. Many roles assume daily travel across Johannesburg, Pretoria, or Ekurhuleni. Before you apply, estimate taxi, bus, or fuel costs so a job that looks well paid on paper still makes sense after commuting.
This role is posted by Hire Resolve. Verify all details, qualifications, and application steps on the official listing before applying.
Applying for permanent roles
- Mirror the job title and top three requirements in your CV summary and most recent experience.
- Quantify results where possible: sales targets, cases handled, tickets closed, or team size.
- Proofread contact details and filenames before submitting — small errors cost interviews.
- Verify the company and role on the source page before sharing ID copies or banking details.
Need broader help? Read our job scam safety guide and editorial policy.
The full posting may include additional requirements. .